Prediction of long-term patient outcome after contemporary left main stenting using the SYNTAX and SYNTAX II scores: A comparative analysis from the FAIL-II multicenter registry (failure in left main study with 2nd generation stents-Cardiogroup III study)
Catheterization and Cardiovascular Interventions Sep 12, 2019
Cerrato E, Barbero U, Quadri G, et al. - Researchers assessed SYNTAX Score-II (SS-II) for its ability to predict long-term mortality in patients who underwent left main PCI (LM-PCI) using second-generation drug-eluting stents. In the FAILS-2 registry, they examined 804 patients for whom they calculated the SYNTAX score (SS) and the SS-II. They grouped patients in low (SS-II ≤ 33; n = 278, 34.6%), intermediate (SS-II 34–43; n = 260, 32.3%) and high (SS-II ≥ 44; n = 266, 33.1%) SS-II tertiles. All-cause mortality was assessed as a primary endpoint. With regard to the ability to predict outcomes related to contemporary LM-PCI, the SS-II was found superior to the SS. Additional markers of poor outcome were acute coronary syndrome and T2DM, which are two clinical variables not incorporated in the SS-II.
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