van Dijkhuizen EHP, et al. - Authors predicted the occurrence of inactive disease in juvenile idiopathic arthritis in the first 2 years of disease. Probably because of disease heterogeneity, inactive disease could not be predicted with satisfactory accuracy in the whole cohort. Experts noted the presence of interesting predictors in more homogeneous subgroups. The following factors predicted the inactive disease: lower baseline juvenile arthritis DAS (JADAS)-71 and lower relative abundance of the operational taxonomic unit Mogibacteriaceae for oligoarticular patients; shorter duration of morning stiffness, higher haemoglobin and lower CXCL-9 levels at baseline for polyarticular RF negative patients; and shorter duration of morning stiffness and higher baseline haemoglobin for ANA positive patients.