Al-Kadi OS., et al. - Researchers determined if tumor stage and uptake on ¹⁸F-fluorodeoxyglucose positron emission tomography are predicted by the fractal dimension (FD) of non-small cell lung cancer (NSCLC) on CT. A box counting algorithm was employed to ascertain the FD within a tumor region, which was then compared with the lymph node and metastatic involvement and overall stage as ascertained from PET. Per results, advanced stage and greater FDG uptake on PET were reported in correlation with higher FD in CT images of NSCLC. The potential application of measurements of tumor fractal analysis on conventional non-contrast CT examinations was suggested as a prognostic marker and/or to pick patients for PET.