Prediction of death after noncardiac surgery: Potential advantage of using high‐sensitivity troponin T as a continuous variable
Journal of the American Heart Association Mar 14, 2021
Machado MN, Rodrigues FB, Nakazone MA, et al. - Researchers aimed at comparing the prediction of 30‐day mortality among patients (876) > 40 years of age who underwent noncardiac surgery using continuous postoperative high‐sensitivity cardiac troponin T (hs‐cTnT) levels to the use of the overall upper reference limit (URL) and age‐ and gender‐specific URLs. Measurement of Hs‐cTnT was done on postoperative day 1. Overall mortality of 4.2% was recorded. There was a 0.3% increase in mortality for each 1 ng/L increase in postoperative hs‐cTnT. Hs‐cTnT as a continuous variable was found to be independently related to 30‐day mortality as well as it exhibited the highest accuracy. In addition, Hs‐cTnT elevations using overall and/or age‐ and gender‐specific URLs were linked with greater mortality.
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