Gupta T, Lochan D, Verma N, et al. - Researchers examined the epidemiology as well as the impact of bacterial infections at admission in patients with acute decompensation (AD) of cirrhosis. A cohort of 179 patients with AD was examined; bacterial infections were reported in 102 (56.9%) of these patients at admission. Findings suggest the leading causative role of infections in the occurrence of AD; spontaneous bacterial peritonitis was the most common infection identified, and E. coli was identified to be the commonest microorganism in this single-center study of Indian patients with AD of cirrhosis. Among culture-positive infections, they noted a high prevalence of multidrug-resistant organisms that independently predict 28-day mortality in AD of cirrhosis.