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Predicting the risk of the distant recurrence of cervical cancer after concurrent chemoradiation: A validation study of the Korean Gynecologic Oncologic Group (KGOG)-1024 model

Gynecologic Oncology Oct 27, 2021

Shin W, Park SY, Seo SS, et al. - Evaluation of the performance of the Korean Gynecologic Oncologic Group (KGOG)-1024 risk model in predicting the risk of distant failure after chemoradiation in patients with locally advanced cervical cancer (LACC).

  • Using the KGOG-1024 risk model, researchers calculated individual risk in a retrospective cohort of 297 patients who received treatment with concurrent chemoradiation for advanced cervical cancer and classified the patients into low-, intermediate-, and high-risk groups (27.2%, 49.3%, and 23.5% of patients, respectively).

  • The calculated and observed 5-year cumulative incidence rates were 12.4% vs 16.4%, 23.2% vs 25.9%, and 50.7% vs 36.3% in the three groups, respectively.

  • Overall, distant recurrence after chemoradiation could be accurately predicted in patients with LACC, especially in the low- and intermediate-risk groups, using the KGOG-1024 risk assessment model.

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