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Predicting radiation dosimetric distribution in different regions of the jaw in patients receiving radiotherapy for squamous cell carcinoma of the tonsil

Head & Neck Aug 09, 2019

Tsai CJ, Verma N, Owosho AA, et al. - As dental complications may occur following radiotherapy (RT), the main treatment for patients with head and neck cancer, researchers sought to build two predictive models for ascertaining the expected maximum radiation dose, one for the non-molar regions and another for the molar regions. Data of 244 patients with squamous cell carcinoma of the tonsil who treated with RT from 2004 to 2013 were retrieved. The final model for the non-molars included location, T-classification, and overall stage, with a median absolute prediction error of 7.0 Gy. The final model for the molars included location, T-classification, overall stage, and treatment year, with a median absolute error of 6.0 Gy. A good estimation of the maximum radiation dose delivered to different regions of the jaw could be made using the current model.
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