Iliaz R, et al. - Researchers investigated the 30-day mortality rate of spontaneous bacterial peritonitis (SBP) and their predictors in this investigation. It was observed in the findings that SBP had high 30-day mortality. In patients with SBP, model for end-stage liver disease (MELD) scores and inflammatory markers (C-reactive protein {CRP}, CRP albumin ratio, neutrophil–lymphocyte ratio) could be utilized to anticipate mortality.

Methods

• In this investigation, 70 patients with cirrhosis complicated with SBP and 55 non-SBP controls were recruited, and patients were evaluated for mortality rate and its predictors.

Results

• The study results showed that the 30-day and 3-month mortality rates in the SBP group were 26.1 and 50.7%, respectively.
• As compared to controls, mortality rates were higher in the SBP group.
• In predicting 30-day mortality, symptoms at hospital admission and cell counts in ascitic fluid made no difference.
• It was observed in the findings that patients with SBP with high serum neutrophil counts, high neutrophil–lymphocyte ratio, high CRP/albumin ratio, and high MELD score had higher 30-day mortality rates.
• Optimal cutoff values of MELD scores and serum neutrophil counts for predicting 30-day mortality as 20.5 and 6850/mm3, respectively were determined.
• It was noted that the sensitivity and specificity for the MELD cutoff value were 83.3 and 80.4%, respectively.
• Patients for 60 months after SBP were also followed up.
• Compared with the group with lower levels, patients with high inflammatory markers and MELD scores at the time of SBP diagnosis had worse survival.