Prediagnostic proinflammatory dietary potential is associated with all-cause mortality among African-American women with high-grade serous ovarian carcinoma
The Journal of Nutrition Jun 06, 2019
Peres LC, et al. - Using data from ovarian carcinoma patients (n=490, median age 57 years) enrolled in the African-American Cancer Epidemiology Study, researchers examined if there is a link between diet-associated inflammation (a modifiable source of chronic systemic inflammation measured by the dietary inflammatory index [DII]) and all-cause mortality among African-American women with ovarian carcinoma. Study sample comprised women with late-stage disease and high-grade serous carcinoma in 66% and 64%, respectively. Majority of women were obese (58%). An increased risk of mortality was evident in relation to greater energy-adjusted DII scores including supplements (signifying greater inflammatory potential) among women with high-grade serous carcinoma. Overall, findings revealed a possible adverse influence of greater inflammatory potential of prediagnostic diet on prognosis in African-American women with high-grade serous carcinoma, and particularly among ever smokers.
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