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Prediabetes and risk for cardiovascular disease by hypertension status in black adults: The Jackson Heart Study

Diabetes Care Oct 13, 2019

Hubbard D, Colantonio LD, Tanner RM, et al. - Among 3,313 black adults in the Jackson Heart Study (JHS) without diabetes or a history of cardiovascular disease (CVD) at baseline (2000–2004), researchers explored the connection between prediabetes—defined as fasting plasma glucose levels 100-125 mg/dL or hemoglobin A1c between 5.7% and 6.4% (39 and 46 mmol/mol)—and CVD by hypertension status (systolic/diastolic blood pressure ≥ 140/90 mmHg and/or self-reported antihypertensive medication use). In total, 35% of JHS participants had no prediabetes or hypertension, 18% had prediabetes alone, 22% had hypertension alone, and 25% had both prediabetes and hypertension. In this cohort of black adults, prediabetes was not linked to an increased risk for CVD or all-cause mortality, irrespective of hypertension status.

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