Jamieson EL, Spry EP, Kirke AB, et al. - Researchers aimed at examining if early pregnancy HbA_1c can aid in predicting gestational diabetes mellitus (GDM) and adverse birth outcomes in Australian women. They conducted a prospective study of 466 women without diabetes, aged ≥ 16-years at first antenatal presentation. Among these women, 396 (129 Aboriginal) women underwent routine 75g oral glucose tolerance test (OGTT; ≥ 24-weeks gestation), of whom 28.8% had GDM (24.0% Aboriginal). Per findings, early pregnancy HbA _1c ≥ 5.6% (≥38 mmol/mol) can aid in identifying Aboriginal women with apparent prediabetes and raised risk of having a large-for-gestational-age (LGA) newborn. In this high-risk population, universal HbA_1c at first antenatal presentation could allow earlier management of hyperglycemia and improved perinatal outcome.