Wei Y, Xu Q, Yang H, et al. - Through a population-based retrospective cohort study of 6,447,339 women who were aged 20–49 years old who took part in National Free Pre-Pregnancy Checkups Project and finished pregnancy outcomes follow-up between 2010 and 2016 in China (first and largest population-based cohort study), researchers assessed the relationships between preconception blood fasting plasma glucose (FPG) level and following pregnancy outcomes. Among reproductive-age women, the awareness rate of DM status discovered to be remarkably low in China, and even in individuals who were aware of their DM status, the management of pregestational DM persisted to be deficient. Preconception impaired fasting glucose (IFG) or DM could raise the risk of adverse pregnancy outcomes, comprising spontaneous abortion, preterm birth (PTB), macrosomia, small for gestational age infant (SGA), and perinatal infant death. In conclusion, a greater risk of adverse pregnancy outcomes, like spontaneous abortion, PTB, macrosomia, SGA, and perinatal infant death was observed in women with preconception IFG or DM. Moreover, preconception glycemic control through relevant methods is one of the most significant perspectives of preconception care and shall not be overlooked by policymakers.