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Preconception alcohol consumption and risk of miscarriage in over 4.5 million Chinese women aged 20–49 years

Journal of Family Planning & Reproductive Health Care May 13, 2021

Chai J, Guo T, Deng Y, et al. - Researchers conducted a population-based, retrospective cohort study in China between January 1, 2013, and December 31, 2016, to evaluate the impact of preconception alcohol consumption on the risk of miscarriage incidence, and further assess the relationship between maternal periconception drinking abstinence and miscarriage. In total, 4,531,680 women with available data on preconception alcohol intake and miscarriage were involved in the final analyses. Miscarriage occurred in 2.70% of the 4,531,680 women studied. Preconception alcohol consumption was linked to an increased risk of miscarriage, and both paternal and maternal alcohol consumption was linked to an increased risk. Periconception alcohol abstinence was inversely related to miscarriage.

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