Coelho NH, Coelho A, Augusto R, et al. - Researchers investigated whether preoperative inflammatory biomarkers, specifically the neutrophil to lymphocyte ratio (NLR) and the platelet to lymphocyte ratio, hold value in predicting an adverse result post-revascularisation for acute limb ischaemia (ALI). They retrospectively screened all patients submitted to lower limb revascularisation for Rutherford IIa or IIb ALI between 2009 and 2019. The composite endpoint of 30 day death or amputation was set as the primary outcome. Findings showed an association of higher preoperative NLR with 30 day death or amputation post-intervention for Rutherford grade IIa or IIb ALI. Experts concluded that NLR potentially represents a simple, broadly available as well as inexpensive biomarker with the ability to refine decision making as well as it likely contribute to ALI morbidity and mortality attenuation.