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Pre-operative evaluation of epithelial ovarian cancer patients: Role of whole body diffusion weighted imaging MR and CT scans in the selection of patients suitable for primary debulking surgery. A single-centre study

European Journal of Radiology Jan 25, 2020

Rizzo S, De Piano F, Buscarino V , et al. - Researchers designed a single-centre study to examine the accuracy of Whole Body MRI including Diffusion-Weighted Imaging sequences (WB DWI MR) in the evaluation of sites of disease in epithelial ovarian cancer (EOC), in comparison to CT; to assess whether a clinical-radiological score may predict suboptimal cytoreductive surgery. They recruited a sum of 92 individuals with suspected EOC who underwent pre-operative WB DWI MR. Data recorded included: age, staging, dates of examinations and surgery; tumour markers; sites of disease at imaging scans and at surgery. They investigated the relationship between clinical and radiological criteria with sub-optimal cytoreduction to distinguish a final model to predict sub-optimal cytoreduction. WB DW MRI is accurate for evaluation of multiple sites and it is significantly more accurate than CT for specific unresectable sites in pre-operative evaluation of EOC individuals. For suboptimal cytoreduction, significant sites of disease were mesenteric carcinomatosis, mesenteric retraction and large bowel carcinomatosis.
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