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Pre-hospital mechanical ventilation in septic shock patients

The American Journal of Emergency Medicine Jan 11, 2019

Jouffroy R, et al. – In this study involving septic shock patients requiring mechanical ventilation in the prehospital setting, researchers described the characteristics of prehospital mechanical ventilation. Participants included patients with septic shock subjected to pre-hospital intubation and mechanical ventilation by a mobile intensive care unit. The investigators assessed the relationship between the tidal volume indexed on ideal body weight (VTIBW) and mortality at day 28. Among 59 patients, septic shock was mainly related to pulmonary (64%) infection. In pre-hospital mechanically ventilated patients with septic shock, an association was found between mortality at day 28 and prehospital VTIBW. A VTIBW < 8 ml·kg−1 was associated with a decrease and a VTIBW > 8 ml·kg−1 associated with a mortality increase.

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