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Pre-arrest and intra-arrest prognostic factors associated with survival following traumatic out-of-hospital cardiac arrest–A systematic review and meta-analysis

Resuscitation Jun 12, 2020

Tran A, Fernando SM, Rochwerg B, et al. - Researchers aimed at inscribing the prognostic correlations of pre- and intra-arrest factors with return of spontaneous circulation (ROSC) and survival (in-hospital or 30 days) after traumatic out-of-hospital cardiac arrest. PRISMA and CHARMS guidelines were followed to perform this review. They searched Medline, Pubmed, Embase, Scopus, Web of Science and the Cochrane Database of Systematic Reviews and identified 53 studies involving 37,528 patients for inclusion in this study. Presence of cardiac motion on ultrasound (odds ratio 33.91, 1.87 to 613.42, low certainty) or a shockable initial cardiac rhythm (odds ratio 7.29, 5.09 to 10.44, moderate certainty) was identified as the most important predictors of survival, based on pooled unadjusted analyses. Importantly, no association was observed of mechanism of injury with either ROSC or survival. Very low to moderate certainty evidence were thus gained indicating predictive value of pre- and intra-arrest prognostic factors following penetrating or blunt traumatic OHCA for ROSC and survival.

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