Dodd PJ, et al. - Researchers determined the first global and national estimates of the influence of moving from zero to full coverage of household contact management (with and without preventive therapy for tuberculin skin test (TST)-positive children older than 5 years) in this mathematical modelling study. Given that household contact management aims to identify children with active tuberculosis and to provide preventive therapy for those with HIV or those younger than 5 years. They obtained data on tuberculosis notifications, household structure, household contact co-prevalence of tuberculosis disease and infection. They also took note of the efficacy of preventive therapy, and the natural history of childhood tuberculosis. They observed that, globally, a substantial reduction in childhood disease and death caused by tuberculosis resulted from household contact management.