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Potential effect of age of BCG vaccination on global pediatric tuberculosis mortality: A modelling study

The Lancet Global Health Nov 15, 2019

Roy P, et al. - Age-specific BCG coverage in 152 high-burden countries using data from large, nationally representative household surveys was predicted, to parameterize a static mathematical model, calibrated to global childhood tuberculosis deaths in 2016 in order evaluate the potential global tuberculosis mortality advantage of administering BCG on time and consequences of later administration. It was discovered that decreasing delays and raising coverage at birth would considerably decrease global pediatric tuberculosis mortality. Modeled scenarios whereby BCG was added later in the infant schedule were all supposed to boost tuberculosis deaths, even with progressed coverage. Moreover, the WHO recommendation for BCG at birth should be sustained and affirmed.
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