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Postprandial increase in serum CA125 as a surrogate biomarker for early diagnosis of ovarian cancer

Journal of Translational Medicine May 09, 2018

Gu Z, et al. - Researchers evaluated the postprandial fluctuation pattern of cancer-derived CA125 and the underlying mechanism to explore an effective approach to improve the performance of CA125 in early diagnosis of ovarian cancer. Findings revealed a unique and distinctive postprandial pattern of cancer-derived serum CA125. This pattern might distinguish it from the common CA125 elevation in a benign disease condition. The dynamic measurement/assessment strategy seemed to have a potential for providing a discriminatory power superior to that of a static test.

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