Abou-Arab O, et al. - Given that onset of vasoplegic syndrome (VS) may be associated with overproduction of nitric oxide (NO) and the response of the brachial artery to NO can be assessed using flow-mediated vasodilation (FMD), researchers herein assessed brachial artery diameter and FMD response immediately after cardiac surgery. The NO-mediated endothelial vasomotor response was shown to be altered by cardiac surgery with cardiopulmonary bypass. VS patients vs non-VS patients had greater mean brachial artery diameter on intensive care unit admission.