Porceddu SV, et al. - Whether the addition of concurrent chemotherapy to postoperative radiotherapy (CRT) improved locoregional control in patients with high-risk cutaneous squamous cell carcinoma of the head and neck, was investigated in the Trans Tasman Radiation Oncology Group randomized phase III trial. Excellent freedom from locoregional relapse (FFLRR) was achieved with surgery and postoperative radiotherapy but addition of weekly carboplatin did not provide any benefit.