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Postmortem CT: Is coronary angiography required in the presence of a high coronary artery calcium score?

Clinical Radiology Sep 20, 2019

Robinson C, et al. - Researchers examined whether a high coronary artery score prognosticated that the subsequent postmortem CT (PMCT) with angiography (PMCTA) would diagnose important coronary artery disease (CAD), inquired the diagnostic influence of assuming there was important CAD on the basis of a high coronary artery calcium (CAC) score alone and questioned whether the clinical CAC score threshold (400) was the most reliable to make this prediction. In cases of adult sudden natural death, CAC scoring and PMCTA were done. In 100/104 PMCT examinations and in 87/100 angiography examinations, PMCTA with the CAC score was a success. A CAC score of > 400, the clinical level of severe disease was noted in 46 cases. In 31 of these cases, CAD was presented as the cause of death. In 39 of these cases, angiography was a success and it revealed severe CAD in all but one. Without a high CAC score, 25 cases were diagnosed with CAD death. In conclusion, however, the CAC score could neither diagnose nor eliminate death because of CAD, the addition of angiography adds little diagnostic information to a high CAC score. If PMCT examination is to eliminate trauma and give a medical reason for death on the “balance of probabilities”, angiography is not needed when the calcium score > 400. This could decrease the number of patients needing angiography by approximately 50%.
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