Tezuka J, Sanefuji M, Ninomiya T, et al. - Utilizing data from the Japan Environment and Children's Study, a nationwide government‐funded birth cohort study, researchers sought to determine when during the first year of life cow's milk (CM)‐based formula consumption becomes associated with lower CM allergy (CMA), defined as an allergic reaction to a CM product in an individual not consuming CM products at the time of evaluation, combined with physician‐diagnosed food allergy, risk. This research involves more than 100,000 children across Japan. At 6 and 12 months old, respectively, the prevalence of CMA was 0.23% and 1.03%. Regular exposure to formula milk at 3 months of age or older is associated with lower CMA at 12 months of age, implying that if the exposure is brief, the effect of very early CM exposure on CMA can disappear. However, at present, the findings of this observational study should not be used for formula recommendation and randomized controlled trials are needed to validate this correlation.