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Positive predictive value of diagnostic codes for inflammatory bowel disease in the Danish national patient registry among individuals 50+ years, using patient records as reference standard

Clinical Epidemiology May 30, 2021

Rye C, Rubin KH, Moller FT, et al. - This study sought to confirm the diagnosis of inflammatory bowel diseases (IBD) among patients aged 50+ years in the Danish National Patient Registry (NPR) by comparison with patient medical records. Researchers conducted validation by comparing patient medical records with information on discharge diagnoses of IBD from the NPR. For the analysis, 339 were registered with an IBD diagnosis in NPR, with 277 (82%) records available for review out of 57,053 individuals in the Diet, Cancer, and Health cohort. The findings revealed that the validity of IBD diagnoses in the registry of individuals aged 50+ years elevated with the number of registrations. It is recommended that these outcomes are taken into consideration in further trials, particularly in epidemiology research using NPR as a data source for patients diagnosed with IBD.

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