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Positive expiratory pressure therapy with and without oscillation and hospital length of stay for acute exacerbation of chronic obstructive pulmonary disease

International Journal of COPD Nov 29, 2019

Milan S, Bondalapati P, Megally M, et al. - Among patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease (AECOPD), researchers investigated whether a decrease in hospital length of stay (LOS) can be achieved via therapy with a positive expiratory pressure (PEP) device with or without an oscillatory mechanism (OM) in addition to standard care. They carried out two studies. They performed a prospective trial in patients admitted with AECOPD and sputum production, to compare PEP therapy vs Oscillatory PEP therapy. They also explored the influence of PEP ± OM vs standard care on hospital LOS by comparing a retrospective historical cohort, matched in a 2 to 1 manner by age, gender, and season of admission, vs prospectively gathered data. In patients admitted for AECOPD, a decrease in hospital LOS may be achieved with adjunctive therapy with a PEP device vs standard care. A further decrease in hospital LOS was indicated by the addition of an OM component to PEP therapy.
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