Bethell C, et al. - In this cross-sectional study of 6,188 adults, researchers assessed correlations between adult-reported positive childhood experiences (PCEs) and adult depression and/or poor mental health (D/PMH) and adult-reported social and emotional support (ARSES) across adverse childhood experiences (ACEs) exposure levels. The adjusted odds of D/PMH was 72% lower for adults reporting 6 to 7 vs 0 to 2 PCEs. Odds were 50% lower for those reporting 3 to 5 vs 0 to 2 PCEs. Relations were comparable in magnitude for adults reporting 1, 2 to 3, or 4 to 8 ACEs. The adjusted odds that adults reported “always” on the ARSES variable were 3.53 times bigger for adults with 6 to 7 vs 0 to 2 PCEs. Relations for 3 to 5 PCEs were not important. The PCE relations with D/PMH continued to be stable across each ACEs exposure level when controlling for ARSES. Positive childhood experiences exhibited dose-response relations with D/PMH and ARSES following accounting for exposure to ACEs. The proactive promotion of PCEs for children may decrease the risk for adult D/PMH and promote adult relational health. Joint evaluation of PCEs and ACEs may better target requirements and interventions and facilitate a focus on building strengths to promote well-being. Findings support prioritizing opportunities to promote safe, stable nurturing associations for children that acknowledge the health outcomes of positive experiences.