Elhefnawy ME, Sheikh Ghadzi SM, Tangiisuran B, et al. - A population-based study was conducted to distinguish recurrent ischemic stroke (IS) predictors and to ascertain the possible effect of secondary preventive medications on IS recurrence in non-elderly adults with or without diabetes. Researchers extracted data of 3,386 patients < 60 years old who had a history of index IS from the Malaysian National Neurology Registry from 2009 to 2016. Via SPSS version 22, multivariate logistic regression analysis was performed. In non-elderly adults after the index IS event, IHD was found as the main predictor of IS recurrence, regardless of diabetes status. The data revealed that after index IS, receiving antidiabetic and antiplatelet medications upon discharge were significant predictors of recurrent IS in non-elderly diabetic adults. A randomized clinical trial may be needed to ascertain the effect of secondary preventive medication on IS recurrence, especially in non-elderly adults.