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Poor prognosis and SATB1 overexpression in solid tumors: A meta-analysis

Cancer Management and Research Jun 19, 2018

Wang S, et al. - Considering the previous studies reporting the inconsistent results regarding the prognostic value of special AT-rich sequence-binding protein 1 (SATB1) in solid tumors, a meta-analysis based on 17 studies including 3144 patients was undertaken to search for connections between SATB1 overexpression and overall survival (OS) of patients with solid tumors. Outcomes suggested a significant correlation of high SATB1 reactivity with decreased survival in most cases of solid tumors. Furthermore, SATB1 has been proposed as a promising prognostic biomarker and novel therapeutic target on the basis of its expression level in solid tumors.
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