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Poor outcomes among patients with chronic obstructive pulmonary disease with higher risk for undiagnosed obstructive sleep apnea in the LOTT cohort

Journal of Clinical Sleep Medicine Jan 18, 2019

Donovan LM, et al. - Among people with the chronic obstructive pulmonary disease (COPD), researchers assessed the consequences of intermediate to high risk of undiagnosed obstructive sleep apnea (OSA) using data from the Long Term Oxygen Treatment Trial (LOTT). For this investigation, they compared results with low risk (modified STOP-BANG score < 3) for OSA among those at intermediate to high risk (modified STOP-BANG score ≥ 3). They compared mortality risk or initial hospitalization with proportional hazard models and the incidence of COPD exacerbations with negative binomial regression. Based on the modified STOP-BANG score, 164 (74%) out of the 222 patients studied were assessed as intermediate to high risk for OSA. According to findings, higher risk for undiagnosed OSA was linked to poor outcomes among people with COPD. Increased recognition and management of the OSA could improve the results in this group.

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