Chapa-Rodriguez A, et al. - Experts coveted an investigation of the strength of agreement among abdominal imaging, endoscopic, and histologic findings in pediatric patients complaining of abdominal pain who underwent colonoscopy in order to assess the gastrointestinal tract. Data disclosed suboptimal findings with the strength of agreement among imaging, endoscopic, and histologic analysis. It was noted that colonoscopy and imaging could be required in patients with suspected inflammatory bowel disease. Despite the possible superiority of colonoscopy in the diagnosis of colitis, imaging could impart more information regarding small bowel disease.

Methods

• The scheme of this research was a retrospective chart review.
• The recruitment comprised of pediatric patients who underwent colonoscopy between January 1, 2012, and December 31, 2014, at Women and Children's Hospital of Buffalo.
• Researchers included patients who had abdominal and pelvic CTs or magnetic resonance imaging within 30 days before or after a colonoscopy.

Results

• A total of 102 subjects with a mean age of 12.7 ± 3.8 years were enrolled, 66% were girls.
• Experts analyzed 109 imaging studies, among which 61% of imaging studies were abnormal.
• Colonic wall thickening (CWT) (55%) and colonic wall enhancement (CWH) (24%) were disclosed to be the most frequent intestinal radiological findings.
• It was deduced that free fluid (20%) and fat stranding (18%) were the most common extra-intestinal findings.
• Data revealed that the imaging studies were found to be consistent with histology in 81% and with colonoscopy in 75% with a moderate strength of agreement (k: 0.59 and 0.466, respectively).
• CWT was consistent with histology in 74% with a moderate strength of agreement (k: 0.47).
• As per the outcomes, history of weight loss (OR 5.35, P=0.041), chronic diarrhea (OR 4.22, P=0.014), a positive lactoferrin (OR 7.00, P=0.011), and presence of CWT on imaging study (OR 5.20, P=0.001) served as predictive factors of abnormal histology.