Polybrominated diphenyl ethers, polybrominated biphenyls, and risk of papillary thyroid cancer: A nested case-control study
American Journal of Epidemiology Dec 10, 2019
Huang H, Sjodin A, Chen Y, et al. - Researchers examined the link between serum levels of polybrominated diphenyl ethers and polybrominated biphenyls and papillary thyroid cancer (PTC) in this nested case-control study, by analyzing data from the United States Department of Defense cohort between 2000 and 2013. Overall 742 (341 women and 401 men) histologically verified PTC cases and 742 matched controls were analyzed. In relation to increasing levels of BDE-28, a significantly increased risk of classical PTC was evident in this study. Differences in the risk by gender and tumor size were also evident. The above-mentioned relationship was primarily noted for larger classical PTC (tumor size > 10 mm) with a significantly stronger link in women vs men.
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