Point-of-care HIV viral load testing combined with task shifting to improve treatment outcomes (STREAM): Findings from an open-label, non- inferiority, randomized controlled trial
The Lancet HIV Apr 07, 2020
Drain PK, Dorward J, Violette LR, et al. - Via performing an open-label, non-inferiority, randomized controlled trial in a public clinic in Durban, South Africa, researchers sought to ascertain if adults on antiretroviral therapy (ART) had changed treatment and care outcomes in correlation to receiving point-of-care HIV viral load testing with task shifting vs standard laboratory viral load testing. From Feb 24, 2017, to Aug 23, 2017, 657 participants were screened; of these, 390 were enrolled and randomly assigned to receive either point-of-care viral load testing at enrollment and after 6 months with task shifting to enrolled nurses (intervention group; n = 195), or laboratory viral load testing (standard-of-care group; n = 195). Outcomes revealed significantly improved viral suppression and retention in HIV care in correlation with receiving point-of-care viral load testing combined with task shifting. Treatment may simplify and outcomes may improve using point-of-care testing for HIV-positive adults receiving ART in resource-limited settings.
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