Goldblatt D, et al. - Researchers perform a comparison of the post-booster antibody response in UK infants given a reduced priming schedule of pneumococcal conjugate vaccine (PCV)13 (ie, a 1 + 1 schedule) vs the current 2 + 1 schedule and assess the potential effect on population protection. Observations reveal that post-booster responses in infants primed with a single dose are equivalent or superior for nine of the 13 serotypes in PCV13 to those seen following the standard UK 2 + 1 schedule. It seems that in countries with a mature PCV programme and established herd immunity, introducing a 1 + 1 schedule may maintain population control of vaccine-type pneumococcal disease.