Cardenas JC, et al. - In the present study, researchers examined PROPPR (Pragmatic, Randomized Optimal Platelet and Plasma Ratios) trial to examine the impact of platelet transfusions on mortality in severely injured trauma patients. All-cause mortality at 24 hours and 30 days and hemostasis were primary outcomes. Cause of death, complications, and hospital-, intensive care unit (ICU)–, and ventilator-free days were the included secondary outcomes. In severely injured, bleeding patients, early platelet administration was correlated with improved hemostasis and decreased mortality.