Mao Y, et al. - The goal of this paper was to detect the high-risk patients according to a preoperatively determined signature of the platelet-to-lymphocyte ratio (PLR) of > 193.55, as an indicator of poor treatment outcome in laryngeal squamous cell carcinoma (LSCC) patients. As per findings, poor outcomes were experienced by patients with PLR > 193.55. These patients represented malnutrition and more advanced cancer stage.