Landovitz RJ, et al. - As tenofovir disoproxil fumarate/emtricitabine preexposure prophylaxis (PrEP) is effective against HIV acquisition when taken as prescribed, researchers search for strategies that identify and intervene with those challenged by adherence to daily medication. As per findings, a brief intervention triggered from biomarkers of poor adherence can have a correlation with improved adherence. It seems that drug level monitoring can allow targeting of additional adherence support to those struggling with daily tablet adherence.