Plasma fatty acid-binding protein 4 (FABP4) level is associated with abnormal QTc interval in patients with stable angina and chronic kidney disease
BMC Cardiovascular Disorders Jul 02, 2019
Wang CP, et al. - In patients with stable angina and chronic kidney disease (CKD), researchers determined if there is a link between plasma fatty acid-binding protein 4 (FABP4; also known as adipocyte FABP or adipocyte P2) level and a prolonged QT interval, as assessed via 12-lead electrocardiograms. From a disease management program, 397 consecutive participants having stable angina and CKD were included in this study. Compared to those with borderline and normal QTc intervals, patients with an abnormal QTc interval exhibited significantly greater plasma FABP4 levels. Findings also revealed the correlation of plasma FABP4 levels with QTc prolongation.
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