Anroedh SS, et al. - Researchers performed a median follow-up of 4.7 years in patients with coronary artery disease (CAD) to assess the associations of ten previously identified high risk molecular lipid species and three ceramide ratios with the occurrence of major adverse cardiac events (MACE). They found that in multivariable analyses adjusted for cardiac risk factors, clinical presentation, statin use at baseline, and admission non-HDL cholesterol level, there was an association between Cer(d18:1/16:0) concentration and MACE. They also found that concentrations of Cer(d18:1/16:0), Cer(d18:1/20:0), Cer(d18:1/24:1) and their ratios to Cer(d18:1/24:0) had associations with the composite endpoint death or nonfatal acute coronary syndrome, after multivariable adjustment.