Sanchez M, et al. - The topic of exploration herein was the connection between 8-hydroxy-2'-deoxyguanosine (8-OHdG), a marker of DNA oxidative damage, and end-stage renal disease (ESRD) or death in subjects with type 1 diabetes. An independent relation was disclosed between higher plasma concentrations of 8-OHdG with an increased risk of kidney disease in individuals with type 1 diabetes, which in turn, indicated that this marker could be used to analyze the progression of diabetic kidney disease.