Okano H, et al. – This study was formulated to appraise the capacity of plasma cluster ions (PCIs) to impair the IgE–binding capacity of airborne house dust mite (HDM) allergens under a simulated indoor environmental condition. As per the observations, PCIs exhibited the capacity to impair the IgE–binding capacity of airborne HDM allergens in a simulated environmental condition.

Methods

• HDM extract was atomized as aqueous mist into a cylindrical experimental apparatus filled with PCIs, for the determination of the effects of PCIs on HDM allergens under an experimental condition.
• Dried HDM allergens were floated as airborne particles in an acryl cubic apparatus in the presence of PCIs, for the evaluation of the effects of PCIs under a simulated natural indoor environmental condition.
• ELISA examined the IgE-binding capacities of the PCI- and sham-treated HDM allergens. 

Results

• As compared to that after sham treatment under both experimental and simulated environmental conditions, the IgE-binding capacity of the HDM allergens was significantly impaired after PCI treatment.
• Moreover, the ELISA results demonstrated that the IgE-binding capacities of HDM allergens after PCI treatment showed 68 and 74% reductions compared to those after sham treatment under the experimental and simulated environmental conditions.