Sehgal A, et al. - In this investigation, researchers studied placentae histopathological characteristics in a cohort of preterm growth-restricted infants compared to a cohort of preterm appropriately grown infants. A histopathologist, blinded to the grouping's identity, evaluated placental histopathology in a cohort of 40 preterm infants of 28–32 weeks gestation. Twenty infants had fetal growth restriction (FGR), while 20 were suitable for gestational age (AGA). Based on the Amsterdam Placental Workshop Group Consensus Statement, predefined histopathological features were evaluated. Features that were significantly more common in FGR placentae were maternal vascular malperfusion, accelerated villous maturation and fetal vascular malperfusion. Specific placental histopathological changes may occur in FGR placentae, which may reflect the effects of utero-placental insufficiency, based on the results of the present study.