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Placental function and fetal weight are associated with maternal hemodynamic indices in uncomplicated pregnancies at 35-37 weeks gestation.

American Journal of Obstetrics and Gynecology Jan 24, 2020

Garcia-Gonzalez C, et al. - Researchers screened 1,386 women attending Kings’ College Hospital for routine hospital visit at 35-37 weeks’ gestation in order to ascertain if placental function, perfusion, and fetal weight are correlated with maternal cardiac hemodynamic responses at 35-36 weeks gestation in normal pregnancies. Findings suggest a strong connection between maternal hemodynamic responses and fetoplacental needs across the whole spectrum in normal pregnancies. As per the multivariable analysis, there was a strong correlation of maternal cardiac output and peripheral vascular resistance with placental growth factor which was over and above maternal characteristics and estimated fetal weight. Association of estimated fetal weight with left ventricular mass was noted. Further, the findings emphasize the possible necessity for undertaking a more extensive echocardiographic assessment rather than relying on hemodynamics which are strongly linked with fetoplacental indices for diagnosing maternal cardiac dysfunction in pregnancies complicated by impaired placentation.
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