Soriano AJ, Schnur JB, Harvie HS, et al. - For the treatment of bladder pain syndrome/interstitial cystitis, a hypnosis intervention was found to be feasible, acceptable, safe, and may improve quality of life.

• In this study, 29 out of 30 (96.7%) eligible women were assigned randomly. Furthermore, 12 of 15 (80.0%) individuals completed the 4-week intervention and follow up in the hypnosis group, and 13 of 14 (92.9%) in the usual care group.

• Adherence to the standardized sessions was 80% and participants used the web-based tool for an average of 5.6 ± 2.7 times per week in the hypnosis group.

• During the first two of three planned hypnosis sessions, scores for emotional distress, relaxation, pain severity, and expected bladder symptoms were significantly improved.

• Compared with the usual care group, improvement in quality of life scores was greater in the hypnosis group (−2.6 ± 2.3 vs. −0.9 ± 1.1, p = 0.04).

• No significant between-group differences in urinary symptoms or bladder pain were observed.

• There was no evidence of adverse events.