Cifuentes M, et al. - The effectiveness of pilocarpine and artificial saliva was evaluated and compared as symptomatic treatments for xerostomia and xerophthalmia in cases with Sjogren's Syndrome (SS). For enhancing salivary and lachrymal secretion in patients with SS, pilocarpine was noted to be more efficacious than artificial saliva. It was the first trial that compared the effectiveness of pilocarpine and artificial saliva as treatments for xerostomia and xerophthalmia in SS.