Ross CE, et al. - The researchers sought to quantify the physiologic effects of pre-arrest bolus dilute epinephrine in the Pediatric Intensive Care Unit. It was noted that bolus dilute epinephrine resulted in an increase in systolic blood pressure in the majority of pre-arrest pediatric patients, and lack of blood pressure response was associated with poor outcomes. Compared to responders, non-responders showed higher rates of cardiac arrest or extracorporeal membrane oxygenation within 6 hours and had higher in-hospital mortality.