Doi SAR, Furuya-Kanamori L, Toft E, et al. - In this meta-analysis involving 1,467 adult women, researchers sought to produce consistent evidence regarding the efficacy of physical activity (PA) programs in gestational diabetes mellitus (GDM) prevention to guide clinical practice. PubMed/Medline, ISI Web of Science, Scopus, and EMBASE have been explored to identify the randomized trials published until June 2019. Randomized controlled trials recruiting women at high risk before the 20^th week of gestation comparing the effect of PA interventions with usual care for prevention of GDM have been retrieved. Using a bias-adjusted model of meta-analysis, data obtained were synthesized. The authors discovered that in-facility PA programs begun prior to the 20^th week of gestation can significantly reduce the incidence of GDM among high-risk women.