Phthalates and sex steroid hormones among men from NHANES, 2013-2016
Journal of Clinical Endocrinology and Metabolism Feb 05, 2020
Woodward MJ, et al. - Researchers aimed at examining the relationships between the urinary phthalate metabolites and serum sex steroid hormone concentrations in a nationally representative sample of adult males. From the 2013-2016 National Health and Nutrition Examination Survey performed among 1,420 male participants aged ≥ 20 years, data were retrieved for this cross-sectional analysis. As per results, males may be vulnerable to different phthalate metabolites in age-specific ways. Among men age ≥ 60, there was a correlation of high molecular weight phthalates with lower total, free, and bioavailable testosterone. Particularly, each doubling of Σdi-2-ethylhexyl phthalate (DEHP) was linked with 7.72% lower total testosterone among older men. Among men age 20-39, low molecular phthalates were noted to be linked with lower total, free, and bioavailable testosterone and among men age ≥ 40, Σ1,2-cyclohexane dicarboxylic acid di-isononyl ester (DINCH) was correlated with lower total testosterone.
Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
-
Exclusive Write-ups & Webinars by KOLs
-
Daily Quiz by specialty
-
Paid Market Research Surveys
-
Case discussions, News & Journals' summaries