El Zoghbi M et al. – In the current study, tobacco smoking was shown to be the main factor related to the histologic type of lung cancer and age at the time of diagnosis; occupational exposure to asbestos or silica did not influence the tobacco smoking effect.

Methods

• 7256 males with lung cancer were studied.

Results

• Tobacco smoking was associated with squamous cell carcinoma and small cell carcinomas, and an earlier age at the time of diagnosis.
• Occupatonal exposure to asbestos or crystalline silica did not modify the effect of tobacco smoking on the histologic type of lung cancer or the age at time of diagnosis.
• Neither tobacco smoking nor occupational exposure to asbestos or crystalline silica influenced tumor location.