Plavén-Sigray P, et al. - Given that positron emission tomography (PET) and radioligands binding to the translocator protein (TSPO) represents a potential method for patient stratification and treatment monitoring, researchers here examined if patients with first-episode psychosis and schizophrenia had altered TSPO levels compared to healthy control subjects. Findings revealed that in patients, lower levels of TSPO might correspond to altered function or lower density of brain immune cells.